Normal saline infusion raises blood volume allowing more blood to get to the tissues, organs and brain.

Normal saline also increase cardiovascular performance (increased stroke volume and cardiac output and reduced systemic vascular resistance).

Intermittent saline infusions significantly reduced symptoms and improved quality of life in postural orthostatic tachycardia syndrome (POTS) patients.

Antioxidants glutathione and taurine can reduce oxidative stress and regulate mitochondrial dysfunction which is normally seen in those with chronic fatigue.

Vitamin C assists with iron uptake and transport as well as hormones that affect energy levels.

B vitamins necessary for converting food into energy assist in the mitochondrial respiratory chain.

Carnitine turns fats and food into fuel.

Biotin helps liver utilize glycogen for energy.

CoQ10 supplementation beneficial particularly in those with chronic fatigue syndrome.